Dipotassium Phosphate Dibasic Potassium Phosphate Dibasic BP USP FCC Food grade Analytical Reagent Manufacturers, K2HPO4 |
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Potassium Phosphates Commercial grade
Potassium Phosphate USP BP IP FCC ACS Food Grade Manufacturers
MSDS of Monobasic Potassium Phosphate BP USP NF IP ACS FCC Food Grade Manufacturers
MSDS of Dibasic Potassium Phosphate IP BP USP NF ACS FCC Food Grade Manufacturers
MSDS of Tribasic Potassium Phosphate IP BP USP ACS FCC Food Grade Manufacturers
Potassium Phosphate
Dibasic
Di Potassium Phosphate, Dipotassium Phosphate,
Dibasic Potassium
Phosphate
Dipotassium Phosphate Specifications; Dibasic Potassium Phosphate Dibasic
| Appearance | Fine White Crystals |
| Purity on dry basis | 98% min Dipotassium Phosphate |
| Phosphates as P2O5% | 39.5% min |
| pH of 1% solution | 8.7 - 9.3 |
| Heavy Metals | 10 ppm max |
| Arsenic | 4 ppm max |
| Moisture | 5% max |
| Insoluble | 0.1% max |
Specifications of Dipotassium Hydrogen Phosphate BP Ph Eur
Dipotassium Phosphate BP
K2HPO4 -- 174.2 -- 7758-11-4
Dibasic Potassium Phosphate BP
Potassium Phosphate Dibasic BP
DEFINITION
Dipotassium phosphate contains not less than 98.0 per cent and not
more than the equivalent of 101.0 per cent of K2HPO4,
calculated with reference to the dried substance.
CHARACTERS
A white powder or
colourless crystals, very
hygroscopic, very soluble in water, very slightly soluble in alcohol.
IDENTIFICATION
A. Solution S (see Tests)
is slightly alkaline
B. Solution S gives reaction of
phosphates.
C. Solution S gives reaction of
potassium.
TESTS
Solution S
Dissolve 5.0 g in
distilled water and dilute to 50 ml with
the same solvent.
Appearance of solution
Solution S is clear and colourless.
Reducing substances
Heat on a water-bath for 5 min a mixture of 5 ml
of solution S, 5 ml of dilute sulphuric
acid and 0.25 ml of 0.02 M potassium permanganate. The
solution remains faintly pink.
Chlorides
To 2.5 ml of solution S add 10 ml of
dilute nitric acid and
dilute to 15 ml with water. The solution complies with the limit
test for chlorides (200 ppm).
Sulphates
To 1.5 ml of solution S add 2 ml of
dilute hydrochloric acid and dilute to 15 ml with
distilled
water. The solution complies with the limit test for
sulphates (0.1 per cent).
Arsenic
5 ml of solution S complies with limit test A for arsenic (2
ppm).
Iron
10 ml of solution S complies with the limit test for iron (10
ppm).
Heavy metals
Dissolve 2.0 g in 8 ml of
water. Acidify with about 6 ml of
dilute hydrochloric acid (pH 3 to 4) and dilute to 20 ml with water. 12 ml of the solution complies with limit test A for heavy
metals (10 ppm).
Sodium
If intended for use in the manufacture of
parenteral dosage forms, it contains
not
more than 0.1 per cent of Na, determined by atomic emission
spectrometry.
Loss on drying
Not more than 2.0 per cent, determined on 1.000 g by drying in an
oven at 125C to 130C.
Bacterial endotoxins
Less than 1.1 IU/mg, if intended for use in the manufacture of parenteral dosage forms without a further
appropriate procedure for the removal of bacterial endotoxins.
Dibasic Potassium Phosphate USP
Dipotassium Phosphate USP
Potassium Phosphate Dibasic USP
K2HPO4 174.18
Phosphoric acid, dipotassium
salt.
Dipotassium hydrogen phosphate [7758-11-4].
Dibasic Potassium Phosphate contains not less than 98.0 percent and not more than 100.5 percent of K2HPO4, calculated on the dried basis.
Identification—
A solution (1 in 20)
responds to the tests for Potassium and for Phosphate.
pH: between 8.5 and 9.6, in a solution
(1 in 20).
Loss on drying— Dry it at 105 to constant weight: it loses not
more than 1.0% of its weight.
Insoluble substances— Dissolve 10 g in 100 mL of hot water, filter through a
tarred
filtering crucible, wash the insoluble residue with hot water, and dry
at 105 for 2 hours: the weight of the residue so obtained does not
exceed 20 mg (0.2%).
Carbonate—
To 1 g add 3 mL of water
and 2 mL of 3 N
hydrochloric acid: not more than a few bubbles are evolved.
Chloride— A 1.0-g portion shows no more chloride than corresponds
to 0.40 mL of 0.020 N
hydrochloric acid (0.03%).
Sulfate—
A 0.20-g portion shows no more sulfate than corresponds
to 0.20 mL of 0.020 N
sulfuric acid (0.1%).
Arsenic:
3 ppm.
Iron— the limit is 0.003%.
Sodium— A solution (1 in 10) tested on a platinum wire imparts no
pronounced yellow color to a non-luminous flame.
Heavy metals: the limit is 0.001%.
Limit of fluoride— The limit is 0.001%.
Limit of monobasic or tribasic salt— Dissolve 3 g in 30 mL of water, cool to 20o,
and add 3 drops of thymol blue TS: a blue
color is produced, which is changed to yellow (with a greenish tinge) by
the addition of not more than 0.4 mL of 1 N
hydrochloric acid.
Potassium Phosphate Dibasic FCC
Dipotassium Monophosphate; Dipotassium
Phosphate FCC
Dibasic Potassium Phosphate FCC
K2HPO4 Formula wt 174.18
INS: 340(ii) CAS: [7758-11-4]
DESCRIPTION
Potassium Phosphate, Dibasic, occurs as a colorless or white,
granular salt that is deliquescent when exposed to moist air. One gram
is soluble in about 3 mL of water. It is
insoluble in alcohol. The pH of a 1% solution is about 9.
Function: Buffer;
sequestrant; yeast
food.
REQUIREMENTS
Identification: A 1:20 aqueous solution gives positive tests for
Potassium and for Phosphate.
Assay: Not less than 98.0% of K2HPO4 after drying.
Arsenic: Not more than 3 mg/kg.
Fluoride: Not more than 10 mg/kg.
Insoluble Substances: Not more than 0.2%.
Lead: Not more than 2 mg/kg.
Loss on Drying: Not more than 2.0%.
ACS Specifications
American Chemical Society
Potassium Phosphate Dibasic ACS
Dibasic Potassium Phosphate ACS
Dipotassium Phosphate ACS
Dipotassium Hydrogen Phosphate
K2HPO4
Formula Wt 174.18
CAS Number 7758-11-4
REQUIREMENTS
Assay: 98.0% K2HPO4
pH of a 5% solution:
8.5-9.6 at 25C
MAXIMUM ALLOWABLE
Insoluble matter: 0.01%
Loss on drying at 105C: 1.0%
Chloride (Cl): 0.003%
Nitrogen compounds (as N): 0.001%
Sulfate (SO4): 0.005%
Heavy metals (as Pb): 5
ppm
Iron (Fe): 0.001%
Sodium (Na): 0.05%
Dipotassium phosphate (K2HPO4) - also phosphoric acid, dipotassium salt; dipotassium hydrogen orthophosphate; potassium phosphate, dibasic - is a highly water-soluble salt which is often used as a fertilizer, food additive and buffering agent. It is a common source of phosphorus and potassium. As a food additive, Dipotassium phosphate is on the FDA's Generally recognized as safe, or GRAS, list of substances. It is used in non-dairy creamers to prevent coagulation. The dipotassium salt, K2HPO4 is used alone or in combination with other phosphate compounds as an electrolyte replenisher.
Potassium Phosphate, Dibasic, Anhydrous (K2HPO4) is a reagent with a very high buffering capacity. Widely used in molecular biology, biochemistry, and chromatography. Neutral potassium phosphate buffer solutions may be prepared with a mixture of the monobasic and dibasic forms to varying degrees, depending on the desired pH. Potassium Phosphate buffers are very useful in numerous applications. It has been used to study the effects of freezing and thawing on the stability of proteins sensitive to conformational changes; it was found that KP buffers offered improved pH stability as opposed to NaP buffers. Potassium Phosphate has also been used for the extraction of keratohyalin protein from bovine tissue.
Dibasic Potassium Phosphate Dibasic Dipotassium Phosphate BP USP FCC Food grade Analytical Reagent ACS Manufacturers
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